|
Product Name:Crospovidone
INCI Name:Insoluble PVP
CAS NO.: 9003-39-8
Formula: (C6H9NO)n
Refference:Current USP/NF/EP/BP
Properties: Crospovidone is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.Its; classified as Crospovidone Type A and Type B according to the different particle size.
Key Technical Parameters:
|
Product
|
Crospovidone Type A
|
Crospovidone Type B
|
|
Appearance
|
White or yellowish-white powder or flakes
|
|
Identifications
|
A.Infrared Absorption
|
|
B.No blue color develops.
|
|
C.A Suspension is formed and no clear solution is obtained within 15 min.
|
|
D.Majority of particles are in the range 50 ~300 μm is type A,majority of particles are in the range 5~50 μm
|
|
Solubility
|
Practically insoluble in water,in alcohol and in methylene chloride
|
|
Water- soluble substances
|
1.0% max
|
1.0% max
|
|
pH((1% in water)
|
5.0 –8.0
|
5.0 –8.0
|
|
Loss on Drying
|
5.0% max.
|
5.0% max.
|
|
Sulphated Ash
|
0.1% max.
|
0.1% max.
|
|
Nitrogen content
|
11.0 -12.8 %
|
11.0 -12.8 %
|
|
Impurity A
|
10 ppm max.
|
10 ppm max.
|
|
Peroxide(As H2O2)
|
400 ppm max.
|
1000 ppm max.
|
|
Heavy Metals
|
10 ppm max.
|
10 ppm max.
|
Applications:Crospovidone are widely used as 1)Disintergrating agent,2)Stabilizer for suspension,3)Moisture Absorbent, 4)Complextant of Polyphenols and Tannin for the extract formulations.
|
