Product Name:Crospovidone
INCI Name:Insoluble PVP
CAS NO.: 9003-39-8
Formula: (C6H9NO)n
Refference:Current USP/NF/EP/BP
Properties: Crospovidone is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.Its; classified as Crospovidone Type A and Type B according to the different particle size.
Key Technical Parameters:
Product
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Crospovidone Type A
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Crospovidone Type B
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Appearance
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White or yellowish-white powder or flakes
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Identifications
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A.Infrared Absorption
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B.No blue color develops.
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C.A Suspension is formed and no clear solution is obtained within 15 min.
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D.Majority of particles are in the range 50 ~300 μm is type A,majority of particles are in the range 5~50 μm
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Solubility
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Practically insoluble in water,in alcohol and in methylene chloride
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Water- soluble substances
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1.0% max
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1.0% max
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pH((1% in water)
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5.0 –8.0
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5.0 –8.0
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Loss on Drying
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5.0% max.
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5.0% max.
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Sulphated Ash
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0.1% max.
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0.1% max.
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Nitrogen content
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11.0 -12.8 %
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11.0 -12.8 %
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Impurity A
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10 ppm max.
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10 ppm max.
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Peroxide(As H2O2)
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400 ppm max.
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1000 ppm max.
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Heavy Metals
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10 ppm max.
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10 ppm max.
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Applications:Crospovidone are widely used as 1)Disintergrating agent,2)Stabilizer for suspension,3)Moisture Absorbent, 4)Complextant of Polyphenols and Tannin for the extract formulations.
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