Gamma Polyglutamic Acid

Product Name:Gamma Polyglutamic Acid
Molecular Formula: (C5H7NO3)n

Molecular Structure:
Gamma Poly-glutamic acid (γ-PGA) is a natural occurring, multi-functional, and biodegradable biopolymer. It is produced through fermentation by Bacillus subtilis using glutamic acid. PGA is consists of glutamic acid monomers crosslinked between α-amino and γ-carboxyl groups. It is water-soluble, edible and non-toxictowards human, and is environment friendly. It has broad applications in the fields of medicine, food, cosmetics, and water treatment.

Technical Parameters:


White or Off-White Powder


90.0% min.

pH Value(1% in water)



0.12 max.

Heavy Metals

20 ppm max.

Loss on Drying


Total Plate Count

100 cfu/g





Partice Size

100% through 100 mesh

Applications:γ-PGA widely used in the Pharmaceutical,food industry, cosmetics,water treatment, hygienic products, agriculture and other Hi-tech industries.

Gamma Polyglutamic Acid,first recognized in Japanese food ‘Natto’,it is a natural multifunctional Biopolymer,produced with Bacillus Subtilis by fermentation.

Gamma Polyglutamic Acid(Gamma PGA) is a water soluble homopolymer,it consists of D-Glutamic Acid and L-Glutamic Aid monomers which are connected by amide linkages between α-amino and γ-Carboxyl groups.

Lage number of Carboxyl Groups along the molecule chain of Gamma PGA can form hydrogen bonding in a molecule or between different molecules.Thus it has high water absorbability and moisture retaining capability.Thanks to its unique properties,

Gamma PGA can be used as thickener,filmogen,humcctant,retarder,cosolvent,binder and anti-freezer,therefore,the application prospect of Gamma PGA is promising.


Long-Lasting moisturization

*Possessing high moistureizing capability,much better than Hyaluonic Acid,Collagen.

*Kepping moisture of skin for long time.

*Restoring skin elasticity and smoothening wrinkles.


*Stablizing and increasing HA of skin.

*Increasing NMP of skin.

*Increasing the nutrients absorption of skin.

Healthy Whitening

*Inhibiting melanin biosynthesis.

Long-lasting Moisturization

With strong moisturizing ability, the side chain of gamma PGA can enhance the moisturizing capability of skinwithout breaking moisture balance of skin. When integrated into skin care products, gamma PGA can strengthen the moisturizing ability of skin and prevent skin from drying.

The higher the molecule weight, the stronger the winding effect between molecules. As the molecule network becomes larger, a gamma PGA elastic film will form on the surface of skin.Due to its unique molecule structure, gamma PGA(HM) can absorb and retain skin moisture efficientlyand form a silky film on the surface of skin.It can effectively prevent the skin from long-time drying condition, especially in air-conditioned rooms or in cold dry winter. Gamma PGA enhances skin smoothness, reduces wrinkles and improves elasticity of skin.

The compound of gamma PGA (HM) and gamma PGA (LM) has better moisturizing efficacy. Gamma PGA (HM) can form a protective film on the surface of skin to prevent loss of moisture. Meanwhile,gamma PGA (LM) can nourish skin to deep layer by locking more moisture and nutrients. .

Synergy Effect

Moisture is a key factor to keep the skin healthy. Gamma PGA can not only efficiently increase the moisture of skin, but participate in the metabolic activity of skin to improve the health condition of skin.

Increasing and Maintaining HA of Skin

As a basic component of skin, Hyaluronic Acid (HA) can lock the moisture of the skin and maintain its elasticity,but HA can hydrolyzed very quickly by hyaluronidase of skin as well, Gamma PGA can increase and maintain the content of HA.

Effectively Increasing NMF in Inner Skin

As a hygroscopic material produced by skin, Natural Moisturizing Factor (NMF) provides moisture for skin in cuticle. The NMF including amino acids which are hydrolyzed fromskin matrix protein (e.g.Filament aggregating protein), pyrrolidone carboxylic acid (PCA), lactic acid and urocanic acid (UCA)can retain moisture of skin.

Gamma PGA is the only effective ingredient that is known till now to induce the production of NMF to 130% of the normal level. Gamma PGA can lock the moisture in inner skin by promoting the growth of fibroblast and increasing the content of NMF in horn cells.

Improving Nutrient Supply

Thanks to its controlled release property, gamma PGA can control the release of nutrients and moisture in a continuous manner. Each gamma PGA monomer has ionized groups like α-COOH, -CO and -NH,which can absorb electropositive nutrients. Hence a good embedding deliverysystem is created and active ingredients in cosmetics can possibly maximize their efficacy

Healthy Whitening Efficacy

Gamma PGA can also whiten skin by controlling melanin synthesis to prevent and reduce freckles..Ultraviolet irradiation is the main incentive of tyrosinase, which in tum induces the formation of Melanin.

Applications of Gamma Polyglutamic Acid

As a multifunctional skin care ingredient,Gamma PGA can moisturize and whiten skin and improve skin health.It busilds gentle and tender skin and restore skin cells,

facilitates exfoliation of old keratin.Clears stagnant melanin and gives birth to white and translucent skin.

It has excellent compatibility in non-ionic,anionic and amphoteric surgactants.It is a pefect ingredient for cream,essence,astringent,face mask,eye gel,sun cream,shampoo,

body wash,lotion,hairstyle formula and so on.Gamma PGA is an idea moisturizer with high compatibility with other cosmetics materials.Dosages of the material denpend on the function of the skin care products.Generally suggested dosages of Gamma

PGA(HM) is 0.5%.HM Gamma PGA is more suitable for anti-wrinkle,UV-Preventing and moisturing strengthening products, suggested dosage is 0.1%~1%.LM Gamma PGA is better for facial masks and whitening products,and the suggested dosage is 0.3%.