Alpha-Arbutin (4- Hydroxyphenyl-±-D-glucopyranoside) is a pure, water soluble, biosynthetic active ingredient. Alpha-Arbutin blocks epidermal melanin synthesis by inhibiting enzymatic oxidation of Tyrosine and Dopa. Arbutin appears to have fewer side effects than hydroquinone at similar concentrations – presumably due to the more gradual release. It is the more effective, faster and safer approach to promoting skin-brightening and an even skin tone on all skin types. Alpha-Arbutin also minimizes liver spots and meets all the requirements of a modern skin-brightening and skin depigmentation product.Alpha Arbutin exhibits impressive tyrosinase inhibition and is nine times more effective than Beta-Arbutin. Very low IC50 values indicates the power of  Alpha-Arbutin. The outstanding efficacy of Alphar-Arbutin is due to its perfect affinity to the active site of tyrosinase.Alpha-Arbutin is water soluble and easily incorporated into the water phase of cosmetic formulations. It is stable againsthydrolysis as tested in the pH range from 3.5 – 6.6. Suggested concentration: 0.2% when formulated with an exfoliant or penetration enhancer, otherwise up to 2%.

Key Technical Parameters:

Product Features

• INCI name (active): Alpha-Arbutin
• Scientifically proven effects at low concentrations
• More effective at 1.0% than Beta-Arbutin in vivo
  - Nine times more effective than Beta-Arbutin in vitro
  - Outstanding tyrosinase inhibition activity in vitro
• Highly pure biosynthetic active ingredient
• High performing enzyme related biotechnology
• Does not contain intentionally added substances regulated/listed as preservative
• Halal compliant (porcine and alcohol free, not certified)

Benefits:

• Ensures an even skin tone after only one month
• Reduces the degree of skin tanning after UV exposure
• Helps to minimize the appearance of liver spots